Regional CE Meetings

Clinical Management of the Problem Mare

Instructors: Patrick McCue and Luis Losinno

Location: Kawell Equine Hospital and Rehabilitation Center, Solis, Buenos Aires, Argentina

Date(s): May 20-21, 2025

Clinical Management of the Problem Mare

Key Features

  • Expert faculty: The course will be led by a team of renowned experts in equine reproduction, including Patrick McCue, DVM, PhD, DACT, and Luis Losinno, DVM, PhD.
  • Hands-on training: Participants will have the opportunity to perform diagnostic and therapeutic procedures on live mares.
  • Comprehensive coverage: The course covers a broad spectrum of reproductive issues, including ovarian, uterine, cervical, vaginal, and perineal problems, as well as metabolic and behavioral factors that can affect fertility.
  • Advanced techniques: Participants will learn about cutting-edge techniques such as ultrasound, endoscopy, biopsy, culture, and cytology.
  • Practical application: The course emphasizes the practical application of knowledge through case studies and hands-on exercises

Schedule of Events

Tuesday, May 20

7:45–8:00: Registration; course material pick up
8:00–8:05: Welcome from Alejandro Guglielminetti, DVM; Patrick McCue, DVM, PhD, DACT; and Luis Losinno, DVM, PhD
8:05–9:00: Reproductive evaluation of the problem mare (McCue)
9:00–10:00: The problem mare in commercial breeding programs (Losinno)
10:00–10:30: Coffee break
10:30–11:30: Ovarian and oviductal problems (McCue)
11:30–12:30: Uterine problems and treatment (McCue)
12:30–13:30: Lunch (included in course fee)
13:30–14:45: Laboratory session 1—Different techniques and procedures for endometrial samples (cytology, culture, biopsy) adapted to ambulatory conditions; low volume lavage (LVL) collection and processing
14:45–16:15: Laboratory session 2—Techniques and procedures for culture and antibiograms in situ; pros and cons of doing our own cultures and antibiograms; the reality of doing our own cultures and antibiograms
16:15–16:45: Coffee break
16:45–18:15: Laboratory session 3—Techniques of clinical vaginoscopy and hysteroscopy; the value of vaginoscopy and hysteroscopy as diagnostic tools

Wednesday, May 21

8:00–9:00: Cervical, vaginal, and perineal evaluations (McCue)
9:00–10:00: Advanced knowledge on pregnancy loss in mares (Losinno)
10:00–10:30: Coffee break
10:30–11:00: Behavioral problems (McCue)
11:00–11:30: Mammary gland problems (McCue)
11:30–12:00: Systemic metabolic problems related to reproduction (Losinno)
12:00–12:45: Lunch (included in course fee)
12:45–14:00: Laboratory session 4—Uterine lavage techniques and uterine infusions
14:00–15:15: Laboratory session 5—Uterine cytology and biopsy clinical interpretation; strategic medical decision-making tools in treatment and prognosis
15:15–15:45: Coffee break
15:45–17:00: Laboratory session 6—Clinical analysis and interpretation of cultures and antibiograms
17:00: Question and answer session, closing remarks, and certificates

Speakers

Join us for an exceptional lineup of internationally renowned experts who will share cutting-edge insights into the complex world of challenging mare reproductive health.

Patrick McCue

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Patrick McCue, DVM, PhD, DACT, graduated from the School of Veterinary Medicine at the University of California, Davis (UC Davis). He then completed an internship in large-animal medicine and surgery at the University of Pennsylvania and a residency in equine reproduction at UC Davis. He became a Diplomate of the American College of Theriogenology and earned a PhD in comparative pathology, with an emphasis on reproductive endocrinology and ovarian pathology in mares, at UC Davis. Since 1994, he has been the Iron Rose Ranch Professor of Equine Theriogenology at Colorado State University (CSU; Fort Collins, CO). He coordinates stallion and mare clinical services at the Equine Reproduction Laboratory and handles cases of dystocia, high-risk pregnancies, and other fertility issues at the CSU Veterinary Hospital. McCue is the author or coauthor of 10 books, more than 400 peer-reviewed publications and textbook chapters, and over 200 scientific presentations and abstracts. He has received the Norden Distinguished Teacher Award and the Teaching Award from the American Association of Equine Practitioners, both granted by veterinary students at CSU. In 2017, he was honored as Theriogenologist of the Year by the American College of Theriogenologists for his outstanding contributions to equine theriogenology.

Luis Losinno

Luis Losinno

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Luis Losinno, DVM, PhD, graduated with a DVM from the National University of Río Cuarto (Córdoba, Argentina) and completed his PhD under the mentorship of G. L. Woods at the Northwest Equine Reproduction Laboratory at the University of Idaho[KS1]  (Moscow, ID). He is a tenured professor of equine production (1985–2025) in the Faculty of Agronomy and Veterinary Medicine at the National University of Río Cuarto. Losinno is the director of the Equine Production and Animal Biotechnology Laboratory, former director of the master’s program in equine production at the National University of Río Cuarto, and academic director of the Equine Production Diplomate program (e-quine ACADEMY). He has supervised 11 PhD theses, 12 master’s theses, and more than 350 research assistants and fellows. Additionally, he has directed research projects funded by national, provincial, private, and international organizations. His scientific output (1989–2025) includes more than 120 peer-reviewed abstracts and publications. He has contributed to 18 books and book chapters as editor and co-editor (2009–2025). He has been an invited speaker at over 400 conferences and seminars in Argentina, Chile, Brazil, Uruguay, Peru, Ecuador, Colombia, Mexico, Spain, Portugal, the United States, China, Serbia, Austria, and Qatar. Losinno is a cofounder and first president of the Latin American Society of Animal Reproduction (Sociedad Latinoamericana de Reproducción Animal) and was an organizing committee member of the XIII International Symposium on Equine Reproduction (2023). He is also the cofounder of CARD (Consultants in Animal Research & Development) Solutions, a global consulting firm in research, production, and development programs in animal science (2022), and Equslac, the first donkey milk–production company in Argentina. In 2023, he cofounded and became the academic director of e-quine ACADEMY.

Melina Pietrani

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Melina Pietrani, DVM, MSc, holds a veterinary medicine degree and a master’s in equine production from the National University of Río Cuarto (Córdoba, Argentina). She is currently a doctoral fellow at CONICET, working at the Multidisciplinary Institute for Research and Agro-Food and Biotechnology Transfer (IMITAB-UNVM; Villa María, Argentina). Pietrani serves as a senior lecturer in reproduction at the National University of Villa María and is a member of the academic board of the Equine Production Diplomate program offered by e-quine ACADEMY. Additionally, she teaches postgraduate courses on equine production, facility management, and assisted reproduction in horses. Pietrani has published in international scientific journals such as the Journal of Equine Veterinary Science and the Equine Veterinary Journal. She is also a co-author and editor of books on reproductive biotechnologies in equines. Her research focuses on assisted reproduction, embryo transfer, and equine embryo vitrification. She has participated as a speaker at international congresses and collaborated on research projects related to the production and preservation of donkey milk for human consumption.

Natalia Pallarols

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Natalia Pallarols, DVM, graduated as a veterinarian from the University of El Salvador (Buenos Aires, Argentina) in 2008. She has been an associate professor in the large animal–hospital practice course at the University of El Salvador since 2013. Since 2015, Pallarols has served as the head of the neonatology and internal medicine service at Kawell Equine Hospital and Rehabilitation Center. She also supervises neonatology and internal medicine programs at equine institutions such as Synergy Cloning.